The development of a personalized treatment strategy for patients is a priority area of modern medicine. According to the World Health Organization, the most common non-communicable diseases globally remain cardiovascular diseases (CVD), diabetes mellitus, and obesity. Alongside this, severe psychological trauma and negative emotions accompanying both military personnel and the civilian population during the war can cause not only an increase in the incidence of CVD and cerebrovascular diseases (CeVD) (acute and chronic forms) but also a significant increase in the risk of these conditions in young people, with severe clinical manifestations.

The implementation of this complex research project will contribute to the adoption of European standards for providing medical care to patients with cardiovascular and neurological diseases, as well as illnesses related to the impact of stress factors, through the application of personalized modern treatment and rehabilitation methods, which underscores the relevance of this scientific issue.

In cooperation between the Scientific Department of Internal Medicine and scientists from the V.M. Glushkov Institute of Cybernetics of the National Academy of Sciences (NAS) of Ukraine, work has begun on improving approaches to predicting the course of cardiovascular diseases based on machine learning. Plans include the development of models for diagnosis and prognosis of diseases and their complications, selection of personalized therapy, and development of personal medical technologies for real-time monitoring to assess patients’ conditions. The developed models and software will subsequently be disseminated to data stored by the National Health Service of Ukraine and other national or local departmental registers and databases for implementation into medical practice at the state level.

In 2024, a neurophysiological laboratory was opened in the department, equipped with state-of-the-art diagnostic technology of Ukrainian production, specifically telemedicine software and hardware systems.

The laboratory conducts studies on military personnel and civilians affected by the war: the Cardio-vegetative test (based on mathematical analysis of heart rate variability). This allows for the assessment of the general adaptive potential of neuro-humoral regulation, the involvement of different parts of the autonomic nervous system in regulation, the degree of nervous-emotional tension, the vegetative equivalent of stress, and emotional state, based on a 6-channel electrocardiogram. Also, using original domestic machine algorithms, analysis of subtle changes in the ECG is performed, which may indicate early pre-nosological changes in the myocardium.

The department has conducted work on screening the psycho-emotional health status of Ukrainian women veterans and family members of veterans under a cooperation program with the UN. The department’s scientists participate in international and national congresses, conventions, and conferences with the participation of European colleagues (Poland, Great Britain, Canada, etc.). The department is testing Ukrainian and foreign diagnostic telemedicine software and hardware systems created and manufactured with the participation of Ukrainian scientists from the V.M. Glushkov Institute of Cybernetics of the NAS of Ukraine, the O.O. Bogomolets Institute of Physiology of the NAS of Ukraine, Solvay CJSC (Kyiv, Ukraine), KhAI-Medica (Kharkiv, Ukraine), ISH TECH (Kyiv, Ukraine), Corsano (Netherlands, Switzerland), and CardioLyse (Finland, Ukraine).